The role of hepatocyte apoptosis markers in predicting the histological and serological activity in steatohepatitis

Dados básicos

Código:
Estudo Clínico Académico
Protocolo:
Estudo Clínico Académico
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2021
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Unidades de investigação

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


Helicobacter species binding to the human gastric mucosa

Matos, R; (...); Gärtner, F

Article. 10.1111/hel.12867. 2022


12-Gene Expression Signature: A Potential Key for Predicting Prognosis and Benefit to ACT for Resectable NSCLC Patients

Siqueira, A; (...); Leal, LF

Meeting Abstract. 2023


3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer

José, CS; (...); Oliveira, C

Article. 10.3390/biology12060803. 2023

  • Open Access.

Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects

Ferreira, RM; (...); Figueiredo, C

Article. 10.1093/infdis/jiac397. 2022


Androgen-deprivation therapy and cognitive decline in the NEON-PC prospective study during the COVID-19 pandemic

Araujo, N; (...); Lunet, N.

Article. 10.1016/j.esmoop.2022.100448. 2022

  • Open Access.

Anxiety and Depression in Patients with Prostate Cancer, at Cancer Diagnosis and after a One-Year Follow-Up

Duarte, V; (...); Lunet, N.

Article. 10.3390/ijerph19159122. 2022

  • Open Access.

Association between sociodemographic and clinical features, health behaviors, and health literacy of patients with prostate cancer and prostate cancer prognostic stage

Braga, R; (...); Lunet, N

Article. 10.1097/cej.0000000000000854. 2023


Autoimmune hepatitis and eosinophilia: A rare case report

Garrido, I; (...); Macedo, G.

Article. 10.4254/wjh.v15.i2.311. 2023

  • Open Access.

CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer

Park, Ji-Hyeon; (...); Oliveira, Carla

Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022


CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients

Almeida, GM; (...); Oliveira, C

Article. 10.3390/biomedicines9091249. 2021

  • Open Access.

Clinical databases and extended family pedigrees: the missing tool for intrafamilial risk estimation analysis

Fonseca, Joao; (...); Oliveira, Carla

Meeting Abstract. 2024


Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis

Dal Cero, M; (...); de Manzoni, G

Review. 10.3390/cancers15215191. 2023

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness

Pereira, C; (...); Oliveira, C

Article. 10.1002/ijc.33872. 2022

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness.

Pereira, C; (...); Oliveira, C

Article. 2022


Considerations in comparing intestinal- and diffuse-type gastric adenocarcinomas

Piazuelo, MB, Carneiro, F., Camargo, MC

Letter. 10.1111/hel.12975. 2023


Decellularized Colorectal Cancer Matrices as Bioactive Scaffolds for Studying Tumor-Stroma Interactions

Marques Magalhaes, A; (...); Cardoso, AP

Review. 10.3390/cancers14020359. 2022

  • Open Access.

Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis

Rubin, David T.; (...); Peyrin-Biroulet, Laurent

Article. 10.1093/ibd/izae204. 2024


Deployment of an artificial intelligence tool for precision medicine in ulcerative colitis: Preliminary data from 8 globally distributed clinical sites

Peyrin-Biroulet, L; (...); Kubassova, O

Meeting Abstract. 2023


DEPLOYMENT OF AN ARTIFICIAL INTELLIGENCE TOOL FOR PRECISION MEDICINE IN ULCERATIVE COLITIS: PRELIMINARY DATA FROM 8 GLOBALLY DISTRIBUTED CLINICAL SITES

Rubin, David T.; (...); Kubassova, Olga

Meeting Abstract. 2023


Detection of SARS-CoV-2 infection in thyroid follicular cells from a COVID-19 autopsy series

Macedo, S; (...); Soares Dias Ferreira, A.

Article. 10.1530/ETJ-22-0074. 2022

  • Open Access.

Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population

Matos, R; (...); Oliveira, C

Meeting Abstract. 2023


Dissecting the molecular mechanisms underlying therapy resistance and sensitivity in HER2-positive gastric cancer

Fernandes Neto, Joao M.; (...); Oliveira, Carla

Meeting Abstract. 2024


Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Gu?rin Immunotherapy

Mendes, MH; (...); Santos, L.

Article. 10.7759/cureus.50407. 2023

  • Open Access.

Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Guérin Immunotherapy.

Mendes, MH; (...); santos, l

Article. 2023


EBV and MSI Status in Gastric Cancer: Does It Matter?

do Nascimento, CN; (...); Carneiro, F.

Article. 10.3390/cancers15010074. 2023

  • Open Access.

Engaging European society at the forefront of cancer research and care How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto

Baumann, M; (...); Wilking, N

Article. 10.1002/1878-0261.13423. 2023

  • Open Access.

Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.

Santos, M; (...); Oliveira, C

Article. 2022


Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth

Santos, M; (...); Oliveira, C

Article. 10.3390/biology11071046. 2022

  • Open Access.

Epstein-Barr virus status drives morphological and molecular intra-tumour heterogeneity in gastric cancer: insights from a case report and literature review

Gullo, Irene; (...); Carneiro, Fatima

Article. 10.1007/s00428-025-04035-3. 2025


Exosomal glypican-1 discriminates pancreatic ductal adenocarcinoma from chronic pancreatitis

Moutinho Ribeiro, P; (...); Macedo, G.

Article. 10.1016/j.dld.2021.10.012. 2022

  • Open Access.

Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities

Moutinho-Ribeiro, P; (...); Melo, SA

Article. 10.3748/wjg.v28.i31.4310. 2022

  • Open Access.

Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

Ruivo, CF; (...); Melo, SA

Article. 10.1136/gutjnl-2021-324994. 2022

  • Open Access.

Familial and hereditary gastric cancer, an overview

Carneiro, F

Article. 10.1016/j.bpg.2022.101800. 2022


Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease

De Sousa, H. Tavares; (...); Magro, F.

Meeting Abstract. 2024


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes

Garcia Pelaez, J; (...); Oliveira, C

Article. 10.1016/j.ejmg.2021.104401. 2022


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.

Garcia Pelaez, J; (...); Oliveira, C

Article. 2022


Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Lordick, F; (...); ESMO Guidelines Committee

Article. 10.1016/j.annonc.2022.07.004. 2022

  • Open Access.

Gastric Polyps in Familial Adenomatous Polyposis Portuguese Patients: The First Western Cohort with Asian Features

Baptista, D; (...); Gullo, I

Article. 10.1159/000534571. 2023


Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes

Garcia-Pelaez, J; (...); Oliveira, C

Article. 10.1016/S1470-2045(22)00643-X. 2023

  • Open Access.

Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes

Garcia-Pelaez, J.; (...); Oliveira, Carla

Meeting Abstract. 2024


Hepatic amyloidosis: a prevalence study and clinical characterization of a rare and severe disease

Dias, E; (...); Macedo, G

Article. 10.17235/reed.2022.8622/2022. 2023

  • Open Access.

HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches

Freitas, MB; (...); Duarte, HO

Article. 10.3390/cancers16061227. 2024

  • Open Access.

Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy

Magro, F.; (...); Carneiro, F.

Article. 10.1016/j.cgh.2020.09.017. 2021

  • Open Access.

Histologic Features of Syphilitic Gastritis A Rare but Resurging Imitator of Common Diseases

Assarzadegan, N; (...); Westerhoff, M

Article. 10.1093/ajcp/aqac153. 2023

  • Open Access.

Integrated multi-omics approaches uncover the landscape of gastric cancer in patients with diabetes mellitus

Ferreira, Marta; (...); Oliveira, Carla

Meeting Abstract. 2024


Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis

Papadopoulou, A; (...); Furuta, GT

Article. 10.1097/mpg.0000000000003877. 2024

  • Open Access.

Mechanobiology of Colorectal Cancer

Bras, MM; (...); Granja, PL

Review. 10.3390/cancers14081945. 2022

  • Open Access.

Merging patient-derived iPSCs and organ-on-a-chip technology to disclose the genesis of Hereditary Diffuse Gastric Cancer

Ferreira, Daniel A.; (...); Oliveira, Carla

Meeting Abstract. 2024


Mismatch repair protein and microsatellite instability status in gastric cancer: a comparative study between endoscopic biopsies and surgical specimens

Gullo, I; (...); Carneiro, F

Meeting Abstract. 2022


MISMATCH REPAIR PROTEIN STATUS IN GASTRIC CANCER CAN BE IDENTIFIED IN ENDOSCOPIC BIOPSIES AND DOES NOT SEEM TO INFLUENCE RESPONSE TO PERIOPERATIVE CHEMOTERAPY

Nascimento, Catarina N.; (...); Carneiro, Fatima

Meeting Abstract. 2022


Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

Bordeira-Carrico, R; (...); Bessa, J

Article. 10.1038/s41467-022-29551-7. 2022

  • Open Access.

Performance of immunohistochemical and molecular methods in detecting microsatellite instability in gastric cancer: a multicenter study

Marques, DS; (...); Carneiro, F.

Article. 10.1159/000530997. 2023


Predicting residual neoplasia after a non-curative gastric ESD: validation and modification of the eCura system in the Western setting: the W-eCura score

Morais, R; (...); Santos-Antunes, J

Article. 10.1136/gutjnl-2023-330804. 2023


Presence of Helicobacter Species in Gastric Mucosa of Human Patients and Outcome of Helicobacter Eradication Treatment

Matos, R; (...); Gaertner, F

Article. 10.3390/jpm12020181. 2022

  • Open Access.

Prevalence of Cognitive Impairment before Prostate Cancer Treatment

Ara?jo, N.; (...); Lunet, N.

Article. 10.3390/cancers14051355. 2022

  • Open Access.

Primary gastric choriocarcinoma: a rare and aggressive gastrointestinal malignancy

Dias, E; (...); Macedo, G.

Letter. 10.17235/reed.2022.9433/2022. 2023

  • Open Access.

Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression

Moreira, AM; (...); Seruca, R

Article. 10.3389/fmolb.2022.818552. 2022

  • Open Access.

Real-world data of perioperative FLOT in resectable gastric and gastro-esophagic junction cancer: The experience of a Portuguese institution

Vilas-Boas, M.; (...); Fragoso, M.

Meeting Abstract. 10.1016/j.annonc.2022.04.376. 2022

  • Open Access.

Reproducibility of a 12-gene set for predicting outcome and benefit from ACT in earlystage NSCLC patients

Siqueira, Alexia Polo; (...); Reis, Rui

Meeting Abstract. 10.1183/13993003.congress-2023.OA1451. 2023


Retrospective analysis of the outcomes of endoscopic submucosal dissection for the diagnosis and treatment of subepithelial lesions in a center with high expertise

Santos-Antunes, J; (...); Macedo, G

Article. 10.20524/aog.2021.0675. 2022

  • Open Access.

Role of Endoscopic Biopsies and Morphologic Features in Predicting Microsatellite Instability Status in Gastric Cancer : A Multicenter Comparative Study of Endoscopic Biopsies and Surgical Specimens

Silva, R; (...); Gullo, I

Article. 10.1097/PAS.0000000000002085. 2023


The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing

Barbosa Matos, R; (...); Oliveira, C

Article. 10.3390/cancers13174464. 2021

  • Open Access.

The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence

Freitas, JA; (...); Machado, J.

Article. 10.3390/ijms22189791. 2021

  • Open Access.

The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction

Melo, S; (...); Travasso, DM

Article. 10.1038/s42003-023-05482-x. 2023

  • Open Access.

THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING

Barbosa-Matos, R; (...); Oliveira, C

Meeting Abstract. 2022


The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Van Schooten, TS; (...); Fleitas, T

Article. 10.1186/s12885-022-09689-9. 2022

  • Open Access.

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.

Van Schooten, TS; (...); Fleitas, T

Article. 2022


The Porto European Cancer Research Summit 2021

Ringborg, U; (...); Zitvogel, L

Article. 10.1002/1878-0261.13078. 2021

  • Open Access.

Understanding progression of strictures in ileal Crohn's disease-The importance of setting methodological standards

de Sousa, HT, Carneiro, F.

Editorial Material. 10.1002/ueg2.12327. 2022

  • Open Access.

Validation of a 5-gene signature for predicting outcomes in early-stage NSCLC patients

Miranda, Keila Cristina; (...); Reis, Rui

Meeting Abstract. 10.1183/13993003.congress-2023.OA1449. 2023


Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience

Santos-Antunes, J; (...); Macedo, G.

Article. 10.1097/MEG.0000000000002047. 2021


The Role Of Hepatocyte Apoptosis Markers In Predicting The Histological And Serological Activity In Steatohepatitis

Projeto de fim de curso

Colaboradores: Maria de Fátima Machado Henriques Carneiro


The Role Of Hepatocyte Apoptosis Markers In Predicting The Histological And Serological Activity In Steatohepatitis

Dissertação de Mestrado

Colaboradores: Maria de Fátima Machado Henriques Carneiro


Campos de estudo

Partilhar