The role of hepatocyte apoptosis markers in predicting the histological and serological activity in steatohepatitis

Dados básicos

Código:
Estudo Clínico Académico
Protocolo:
Estudo Clínico Académico
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2021
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Unidades de investigação

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


Helicobacter species binding to the human gastric mucosa

Matos, R; (...); Gärtner, F

Article. 10.1111/hel.12867. 2022


12-Gene Expression Signature: A Potential Key for Predicting Prognosis and Benefit to ACT for Resectable NSCLC Patients

Siqueira, A; (...); Leal, LF

Meeting Abstract. 2023


3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer

José, CS; (...); Oliveira, C

Article. 10.3390/biology12060803. 2023

  • Open Access.

Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects

Ferreira, RM; (...); Figueiredo, C

Article. 10.1093/infdis/jiac397. 2022


Androgen-deprivation therapy and cognitive decline in the NEON-PC prospective study during the COVID-19 pandemic

Araujo, N; (...); Lunet, N.

Article. 10.1016/j.esmoop.2022.100448. 2022

  • Open Access.

Anxiety and Depression in Patients with Prostate Cancer, at Cancer Diagnosis and after a One-Year Follow-Up

Duarte, V; (...); Lunet, N.

Article. 10.3390/ijerph19159122. 2022

  • Open Access.

Association between sociodemographic and clinical features, health behaviors, and health literacy of patients with prostate cancer and prostate cancer prognostic stage

Braga, R; (...); Lunet, N

Article. 10.1097/cej.0000000000000854. 2023


Autoimmune hepatitis and eosinophilia: A rare case report

Garrido, I; (...); Macedo, G.

Article. 10.4254/wjh.v15.i2.311. 2023

  • Open Access.

CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer

Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022


CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients

Almeida, GM; (...); Oliveira, C

Article. 10.3390/biomedicines9091249. 2021

  • Open Access.

Clinical databases and extended family pedigrees: the missing tool for intrafamilial risk estimation analysis

Meeting Abstract. 2024


Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis

Dal Cero, M; (...); de Manzoni, G

Review. 10.3390/cancers15215191. 2023

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness

Pereira, C; (...); Oliveira, C

Article. 10.1002/ijc.33872. 2022

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness.

Article. 2022


Considerations in comparing intestinal- and diffuse-type gastric adenocarcinomas

Piazuelo, MB, Carneiro, F., Camargo, MC

Letter. 10.1111/hel.12975. 2023


Decellularized Colorectal Cancer Matrices as Bioactive Scaffolds for Studying Tumor-Stroma Interactions

Marques Magalhaes, A; (...); Cardoso, AP

Review. 10.3390/cancers14020359. 2022

  • Open Access.

Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis

Article. 10.1093/ibd/izae204. 2024


Deployment of an artificial intelligence tool for precision medicine in ulcerative colitis: Preliminary data from 8 globally distributed clinical sites

Peyrin-Biroulet, L; (...); Kubassova, O

Meeting Abstract. 2023


DEPLOYMENT OF AN ARTIFICIAL INTELLIGENCE TOOL FOR PRECISION MEDICINE IN ULCERATIVE COLITIS: PRELIMINARY DATA FROM 8 GLOBALLY DISTRIBUTED CLINICAL SITES

Meeting Abstract. 2023


Detection of SARS-CoV-2 infection in thyroid follicular cells from a COVID-19 autopsy series

Macedo, S; (...); Soares Dias Ferreira, A.

Article. 10.1530/ETJ-22-0074. 2022

  • Open Access.

Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population

Matos, R; (...); Oliveira, C

Meeting Abstract. 2023


Dissecting the molecular mechanisms underlying therapy resistance and sensitivity in HER2-positive gastric cancer

Meeting Abstract. 2024


Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Gu?rin Immunotherapy

Article. 10.7759/cureus.50407. 2023

  • Open Access.

Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Guérin Immunotherapy.

Article. 2023


EBV and MSI Status in Gastric Cancer: Does It Matter?

do Nascimento, CN; (...); Carneiro, F.

Article. 10.3390/cancers15010074. 2023

  • Open Access.

Engaging European society at the forefront of cancer research and care How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto

Baumann, M; (...); Wilking, N

Article. 10.1002/1878-0261.13423. 2023

  • Open Access.

Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.

Article. 2022


Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth

Santos, M; (...); Oliveira, C

Article. 10.3390/biology11071046. 2022

  • Open Access.

Epstein-Barr virus status drives morphological and molecular intra-tumour heterogeneity in gastric cancer: insights from a case report and literature review

Article. 10.1007/s00428-025-04035-3. 2025


Exosomal glypican-1 discriminates pancreatic ductal adenocarcinoma from chronic pancreatitis

Moutinho Ribeiro, P; (...); Macedo, G.

Article. 10.1016/j.dld.2021.10.012. 2022

  • Open Access.

Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities

Moutinho-Ribeiro, P; (...); Melo, SA

Article. 10.3748/wjg.v28.i31.4310. 2022

  • Open Access.

Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression

Ruivo, CF; (...); Melo, SA

Article. 10.1136/gutjnl-2021-324994. 2022

  • Open Access.

Familial and hereditary gastric cancer, an overview

Carneiro, F

Article. 10.1016/j.bpg.2022.101800. 2022


Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease

Meeting Abstract. 2024


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes

Garcia Pelaez, J; (...); Oliveira, C

Article. 10.1016/j.ejmg.2021.104401. 2022


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.

Article. 2022


Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Lordick, F; (...); ESMO Guidelines Committee

Article. 10.1016/j.annonc.2022.07.004. 2022

  • Open Access.

Gastric Polyps in Familial Adenomatous Polyposis Portuguese Patients: The First Western Cohort with Asian Features

Baptista, D; (...); Gullo, I

Article. 10.1159/000534571. 2023


Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes

Garcia-Pelaez, J; (...); Oliveira, C

Article. 10.1016/S1470-2045(22)00643-X. 2023

  • Open Access.

Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes

Meeting Abstract. 2024


Hepatic amyloidosis: a prevalence study and clinical characterization of a rare and severe disease

Dias, E; (...); Macedo, G

Article. 10.17235/reed.2022.8622/2022. 2023

  • Open Access.

HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches

Article. 10.3390/cancers16061227. 2024

  • Open Access.

Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy

Magro, F.; (...); Carneiro, F.

Article. 10.1016/j.cgh.2020.09.017. 2021

  • Open Access.

Histologic Features of Syphilitic Gastritis A Rare but Resurging Imitator of Common Diseases

Assarzadegan, N; (...); Westerhoff, M

Article. 10.1093/ajcp/aqac153. 2023

  • Open Access.

Integrated multi-omics approaches uncover the landscape of gastric cancer in patients with diabetes mellitus

Meeting Abstract. 2024


Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis

Article. 10.1097/mpg.0000000000003877. 2024

  • Open Access.

Mechanobiology of Colorectal Cancer

Bras, MM; (...); Granja, PL

Review. 10.3390/cancers14081945. 2022

  • Open Access.

Merging patient-derived iPSCs and organ-on-a-chip technology to disclose the genesis of Hereditary Diffuse Gastric Cancer

Meeting Abstract. 2024


Mismatch repair protein and microsatellite instability status in gastric cancer: a comparative study between endoscopic biopsies and surgical specimens

Gullo, I; (...); Carneiro, F

Meeting Abstract. 2022


MISMATCH REPAIR PROTEIN STATUS IN GASTRIC CANCER CAN BE IDENTIFIED IN ENDOSCOPIC BIOPSIES AND DOES NOT SEEM TO INFLUENCE RESPONSE TO PERIOPERATIVE CHEMOTERAPY

Meeting Abstract. 2022


Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers

Bordeira-Carrico, R; (...); Bessa, J

Article. 10.1038/s41467-022-29551-7. 2022

  • Open Access.

Performance of immunohistochemical and molecular methods in detecting microsatellite instability in gastric cancer: a multicenter study

Marques, DS; (...); Carneiro, F.

Article. 10.1159/000530997. 2023


Predicting residual neoplasia after a non-curative gastric ESD: validation and modification of the eCura system in the Western setting: the W-eCura score

Morais, R; (...); Santos-Antunes, J

Article. 10.1136/gutjnl-2023-330804. 2023


Presence of Helicobacter Species in Gastric Mucosa of Human Patients and Outcome of Helicobacter Eradication Treatment

Matos, R; (...); Gaertner, F

Article. 10.3390/jpm12020181. 2022

  • Open Access.

Prevalence of Cognitive Impairment before Prostate Cancer Treatment

Ara?jo, N.; (...); Lunet, N.

Article. 10.3390/cancers14051355. 2022

  • Open Access.

Primary gastric choriocarcinoma: a rare and aggressive gastrointestinal malignancy

Dias, E; (...); Macedo, G.

Letter. 10.17235/reed.2022.9433/2022. 2023

  • Open Access.

Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression

Moreira, AM; (...); Seruca, R

Article. 10.3389/fmolb.2022.818552. 2022

  • Open Access.

Real-world data of perioperative FLOT in resectable gastric and gastro-esophagic junction cancer: The experience of a Portuguese institution

Meeting Abstract. 10.1016/j.annonc.2022.04.376. 2022

  • Open Access.

Reproducibility of a 12-gene set for predicting outcome and benefit from ACT in earlystage NSCLC patients

Meeting Abstract. 10.1183/13993003.congress-2023.OA1451. 2023


Retrospective analysis of the outcomes of endoscopic submucosal dissection for the diagnosis and treatment of subepithelial lesions in a center with high expertise

Santos-Antunes, J; (...); Macedo, G

Article. 10.20524/aog.2021.0675. 2022

  • Open Access.

Role of Endoscopic Biopsies and Morphologic Features in Predicting Microsatellite Instability Status in Gastric Cancer : A Multicenter Comparative Study of Endoscopic Biopsies and Surgical Specimens

Silva, R; (...); Gullo, I

Article. 10.1097/PAS.0000000000002085. 2023


The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing

Barbosa Matos, R; (...); Oliveira, C

Article. 10.3390/cancers13174464. 2021

  • Open Access.

The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence

Freitas, JA; (...); Machado, J.

Article. 10.3390/ijms22189791. 2021

  • Open Access.

The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction

Melo, S; (...); Travasso, DM

Article. 10.1038/s42003-023-05482-x. 2023

  • Open Access.

THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING

Barbosa-Matos, R; (...); Oliveira, C

Meeting Abstract. 2022


The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Van Schooten, TS; (...); Fleitas, T

Article. 10.1186/s12885-022-09689-9. 2022

  • Open Access.

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.

Article. 2022


The Porto European Cancer Research Summit 2021

Ringborg, U; (...); Zitvogel, L

Article. 10.1002/1878-0261.13078. 2021

  • Open Access.

Understanding progression of strictures in ileal Crohn's disease-The importance of setting methodological standards

de Sousa, HT, Carneiro, F.

Editorial Material. 10.1002/ueg2.12327. 2022

  • Open Access.

Validation of a 5-gene signature for predicting outcomes in early-stage NSCLC patients

Meeting Abstract. 10.1183/13993003.congress-2023.OA1449. 2023


Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience

Santos-Antunes, J; (...); Macedo, G.

Article. 10.1097/MEG.0000000000002047. 2021


The Role Of Hepatocyte Apoptosis Markers In Predicting The Histological And Serological Activity In Steatohepatitis

Projeto de fim de curso

Colaboradores: Maria de Fátima Machado Henriques Carneiro


The Role Of Hepatocyte Apoptosis Markers In Predicting The Histological And Serological Activity In Steatohepatitis

Dissertação de Mestrado

Colaboradores: Maria de Fátima Machado Henriques Carneiro


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