Unravelling Helicobacter pylori strategies to disrupt cell-cell junctions
Dados básicos
- Código:
- Estudo Clínico Académico (Helicobacter)
- Protocolo:
- Estudo Clínico Académico (Helicobacter)
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2019
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays
Silva, LM; (...); Palma, AS
Article. 10.1016/j.carbpol.2020.117350. 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity
Marques, MS; (...); Figueiredo, C.
Article. 10.1080/19490976.2021.1921928. 2021
A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass
Pereira-Marques, J, Ferreira, RM, Figueiredo, C.
Article. 10.1080/19490976.2024.2323235. 2024
A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass.
Pereira-Marques, J, Ferreira, RM, Figueiredo, C
Article. 2024
A review of machine learning methods for cancer characterization from microbiome data
Teixeira, M; (...); Oliveira, HP
Article. 10.1038/s41698-024-00617-7. 2024
A review of machine learning methods for cancer characterization from microbiome data.
Teixeira, M; (...); Oliveira, HP
Review. 2024
Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects
Ferreira, RM; (...); Figueiredo, C
Article. 10.1093/infdis/jiac397. 2022
Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19
Salvador, P; (...); Malheiro, L
Article. 10.7759/cureus.13687. 2021
Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19.
Salvador, P; (...); Malheiro, L
Article. 2021
Combining nucleic acid mimics and spectral imaging with fluorescence in situ hybridization for the analysis of the gastric micro-biogeography
Azevedo, A. S.; (...); Azevedo, N.
Meeting Abstract. 2019
Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori
Ferreira, R; (...); Melo, LDR
Article. 10.3390/ijms23147885. 2022
Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori.
Ferreira, R; (...); Melo, LDR
Article. 2022
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner
Pereira, J; (...); Figueiredo, J
Article. 10.1186/s12964-024-01532-x. 2024
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner.
Pereira, J; (...); Figueiredo, J
Article. 2024
Engineered liposomes to deliver nucleic acid mimics in Escherichia coli.
Moreira, L; (...); Azevedo, NF
Article. 2023
Engineered liposomes to deliver nucleic acid mimics in Escherichia coli
Moreira, L; (...); Azevedo, N.
Article. 10.1016/j.jconrel.2023.02.012. 2023
Enhancing Patient Safety and Access to Care to Populations at Risk of Exclusion: The Example of the Portuguese-Speaking Migrant Community in South London
Figueiredo, C; (...); Neves, A.AB -
Article. 10.20344/amp.12196. 2020
Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing
Pinto Ribeiro, I; (...); Figueiredo, C.
Article. 10.3390/ijms21031096. 2020
Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing.
Pinto Ribeiro, I; (...); Figueiredo, C
Article. 2020
Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci
Cavadas, B; (...); Pereira, L
Article. 10.3390/microorganisms8081196. 2020
Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci.
Cavadas, B; (...); Pereira, L
Article. 2020
H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line
Malesp?n Benda?a, W; (...); Ram?rez, V
Article. 10.1007/s42770-023-00940-4. 2023
H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line.
Malespín Bendaña, W; (...); Ramírez, V
Article. 2023
Harnessing the Microbiome to Reduce Pancreatic Cancer Burden
Bastos, AR; (...); Figueiredo, C.
Review. 10.3390/cancers15092629. 2023
Harnessing the Microbiome to Reduce Pancreatic Cancer Burden.
Bastos, AR; (...); Figueiredo, C
Review. 2023
Helicobacter pylori infection: from standard to alternative treatment strategies
Sousa, C; (...); Melo, LDR
Article. 10.1080/1040841x.2021.1975643. 2022
Helicobacter pylori infection: from standard to alternative treatment strategies.
Sousa, C; (...); Melo, LDR
Review. 2022
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays.
Silva, LM; (...); Palma, AS
Article. 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.
Marques, MS; (...); Figueiredo, C
Article. 2021
Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions
Leite, M; (...); Figueiredo, C.
Article. 10.3390/cells9020513. 2020
Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions.
Leite, M; (...); Figueiredo, C
Article. 2020
Integrin beta 1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.
Figueiredo, J; (...); Seruca, R
Article. 2022
Integrin ß1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells
Figueiredo, J; (...); Seruca, R
Article. 10.1007/s10120-021-01239-9. 2022
Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium
Melo, J; (...); Leite, M
Article. 10.3389/fmicb.2021.654193. 2021
Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium.
Melo, J; (...); Leite, M
Article. 2021
Machine learning-based approaches for cancer prediction using microbiome data.
Freitas, P; (...); Oliveira, HP
Article. 2023
Recent insights into the use of immune checkpoint inhibitors in gastric cancer
Rodrigues, S, Figueiredo, C.
Article. 10.1097/j.pbj.0000000000000162. 2022
Recent insights into the use of immune checkpoint inhibitors in gastric cancer.
Rodrigues, S, Figueiredo, C
Article. 2022
Review: Pathogenesis of Helicobacter pylori infection
Camargo, MC, Figueiredo, C., Machado, J.
Review. 10.1111/hel.12642. 2019
Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution
Bruno Cavadas; (...); Lu?sa Pereira
Article. 10.3390/microorganisms9020240. 2021
Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution.
Cavadas, B; (...); Pereira, L
Article. 2021
Systematic review: gastric microbiota in health and disease
Rajilic Stojanovic, M; (...); Hold, GL
Review. 10.1111/apt.15650. 2020
Systematic review: gastric microbiota in health and disease.
Rajilic Stojanovic, M; (...); Hold, GL
Review. 2020
The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes.
Thorell, K; (...); Rabkin, CS
Article. 2023
The Impact of SARS-CoV-2 Viral Load on the Mortality of Hospitalized Patients: A Retrospective Analysis.
Machado, A; (...); Malheiro, L
Article. 2021
The influence of the gastric microbiota in gastric cancer development
Pereira-Marques, J; (...); Figueiredo, C
Article. 10.1016/j.bpg.2021.101734. 2021
The influence of the gastric microbiota in gastric cancer development.
Pereira Marques, J; (...); Figueiredo, C
Article. 2021
The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally
Van Schooten, TS; (...); Fleitas, T
Article. 10.1186/s12885-022-09689-9. 2022
The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.
Van Schooten, TS; (...); Fleitas, T
Article. 2022
The Role of the Microbiota in Esophageal Cancer
Moreira, C, Figueiredo, C., Ferreira, RM
Article. 10.3390/cancers15092576. 2023
The Role of the Microbiota in Esophageal Cancer.
Moreira, C, Figueiredo, C, Ferreira, RM
Review. 2023
The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review
da Costa, CP; (...); Figueiredo, C.
Article. 10.3390/cancers14143385. 2022
The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review.
da Costa, CP; (...); Figueiredo, C
Review. 2022
Transcriptomic remodeling of gastric cells by Helicobacter pylori outer membrane vesicles
Melo, J; (...); Leite, M
Article. 10.1111/hel.13031. 2023