Unravelling Helicobacter pylori strategies to disrupt cell-cell junctions

Dados básicos

Código:
Estudo Clínico Académico (Helicobacter)
Protocolo:
Estudo Clínico Académico (Helicobacter)
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2019
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Unidades de investigação

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays

Silva, LM; (...); Palma, AS

Article. 10.1016/j.carbpol.2020.117350. 2021

  • Open Access.

Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity

Marques, MS; (...); Figueiredo, C.

Article. 10.1080/19490976.2021.1921928. 2021

  • Open Access.

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass

Article. 10.1080/19490976.2024.2323235. 2024

  • Open Access.

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass.

Article. 2024


A review of machine learning methods for cancer characterization from microbiome data

Article. 10.1038/s41698-024-00617-7. 2024

  • Open Access.

A review of machine learning methods for cancer characterization from microbiome data.

Review. 2024


Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects

Ferreira, RM; (...); Figueiredo, C

Article. 10.1093/infdis/jiac397. 2022


Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19

Salvador, P; (...); Malheiro, L

Article. 10.7759/cureus.13687. 2021

  • Open Access.

Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19.

Article. 2021


Combining nucleic acid mimics and spectral imaging with fluorescence in situ hybridization for the analysis of the gastric micro-biogeography

Meeting Abstract. 2019


Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori

Ferreira, R; (...); Melo, LDR

Article. 10.3390/ijms23147885. 2022

  • Open Access.

Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori.

Article. 2022


E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner

Article. 10.1186/s12964-024-01532-x. 2024

  • Open Access.

E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner.

Article. 2024


Engineered liposomes to deliver nucleic acid mimics in Escherichia coli.

Article. 2023


Engineered liposomes to deliver nucleic acid mimics in Escherichia coli

Moreira, L; (...); Azevedo, N.

Article. 10.1016/j.jconrel.2023.02.012. 2023

  • Open Access.

Enhancing Patient Safety and Access to Care to Populations at Risk of Exclusion: The Example of the Portuguese-Speaking Migrant Community in South London

Figueiredo, C; (...); Neves, A.AB -

Article. 10.20344/amp.12196. 2020

  • Open Access.

Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing

Pinto Ribeiro, I; (...); Figueiredo, C.

Article. 10.3390/ijms21031096. 2020

  • Open Access.

Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing.

Article. 2020


Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci

Cavadas, B; (...); Pereira, L

Article. 10.3390/microorganisms8081196. 2020

  • Open Access.

Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci.

Article. 2020


H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line

Malesp?n Benda?a, W; (...); Ram?rez, V

Article. 10.1007/s42770-023-00940-4. 2023

  • Open Access.

H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line.

Article. 2023


Harnessing the Microbiome to Reduce Pancreatic Cancer Burden

Bastos, AR; (...); Figueiredo, C.

Review. 10.3390/cancers15092629. 2023

  • Open Access.

Harnessing the Microbiome to Reduce Pancreatic Cancer Burden.

Review. 2023


Helicobacter pylori infection: from standard to alternative treatment strategies

Sousa, C; (...); Melo, LDR

Article. 10.1080/1040841x.2021.1975643. 2022

  • Open Access.

Helicobacter pylori infection: from standard to alternative treatment strategies.

Review. 2022


Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays.

Article. 2021


Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.

Article. 2021


Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions

Leite, M; (...); Figueiredo, C.

Article. 10.3390/cells9020513. 2020

  • Open Access.

Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions.

Article. 2020


Integrin beta 1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.

Article. 2022


Integrin ß1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells

Figueiredo, J; (...); Seruca, R

Article. 10.1007/s10120-021-01239-9. 2022

  • Open Access.

Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium

Melo, J; (...); Leite, M

Article. 10.3389/fmicb.2021.654193. 2021

  • Open Access.

Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium.

Article. 2021


Machine learning-based approaches for cancer prediction using microbiome data.

Article. 2023


Recent insights into the use of immune checkpoint inhibitors in gastric cancer

Rodrigues, S, Figueiredo, C.

Article. 10.1097/j.pbj.0000000000000162. 2022


Recent insights into the use of immune checkpoint inhibitors in gastric cancer.

Article. 2022


Review: Pathogenesis of Helicobacter pylori infection

Camargo, MC, Figueiredo, C., Machado, J.

Review. 10.1111/hel.12642. 2019


Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution

Bruno Cavadas; (...); Lu?sa Pereira

Article. 10.3390/microorganisms9020240. 2021

  • Open Access.

Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution.

Article. 2021


Systematic review: gastric microbiota in health and disease

Rajilic Stojanovic, M; (...); Hold, GL

Review. 10.1111/apt.15650. 2020


Systematic review: gastric microbiota in health and disease.

Review. 2020


The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes.

Article. 2023


The Impact of SARS-CoV-2 Viral Load on the Mortality of Hospitalized Patients: A Retrospective Analysis.

Article. 2021


The influence of the gastric microbiota in gastric cancer development

Pereira-Marques, J; (...); Figueiredo, C

Article. 10.1016/j.bpg.2021.101734. 2021


The influence of the gastric microbiota in gastric cancer development.

Article. 2021


The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Van Schooten, TS; (...); Fleitas, T

Article. 10.1186/s12885-022-09689-9. 2022

  • Open Access.

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.

Article. 2022


The Role of the Microbiota in Esophageal Cancer

Moreira, C, Figueiredo, C., Ferreira, RM

Article. 10.3390/cancers15092576. 2023

  • Open Access.

The Role of the Microbiota in Esophageal Cancer.

Review. 2023


The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review

da Costa, CP; (...); Figueiredo, C.

Article. 10.3390/cancers14143385. 2022

  • Open Access.

The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review.

Review. 2022


Transcriptomic remodeling of gastric cells by Helicobacter pylori outer membrane vesicles

Melo, J; (...); Leite, M

Article. 10.1111/hel.13031. 2023


Evaluation Of The Use Of Helicobacter Pylori Genotypes And Gastric Microbiota Markers To Identify Individuals At High Risk Of Gastric Carcinoma

Tese de doutoramento

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Harnessing The Microbiome To Reduce Pancreatic Cancer Burden

Trabalho final de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Helicobacter Pylori Eradication For Gastric Cancer Prevention

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Immune Checkpoint Inhibitors For The Treatment Of Gastric Cancer

Trabalho final de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Immune Checkpoint Inhibitors For The Treatment Of Gastric Cancer

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Systematic Review: The Mucosa-Associated Microbiota In Colorectal Cancer

Projeto de fim de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Systematic Review: The Mucosa-Associated Microbiota In Colorectal Cancer

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


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