Unravelling Helicobacter pylori strategies to disrupt cell-cell junctions

Dados básicos

Código:
Estudo Clínico Académico (Helicobacter)
Protocolo:
Estudo Clínico Académico (Helicobacter)
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2019
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Unidades de investigação

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays

Silva, LM; (...); Palma, AS

Article. 10.1016/j.carbpol.2020.117350. 2021

  • Open Access.

Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity

Marques, MS; (...); Figueiredo, C.

Article. 10.1080/19490976.2021.1921928. 2021

  • Open Access.

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass

Pereira-Marques, J, Ferreira, RM, Figueiredo, C.

Article. 10.1080/19490976.2024.2323235. 2024

  • Open Access.

A metatranscriptomics strategy for efficient characterization of the microbiome in human tissues with low microbial biomass.

Pereira-Marques, J, Ferreira, RM, Figueiredo, C

Article. 2024


A review of machine learning methods for cancer characterization from microbiome data

Teixeira, M; (...); Oliveira, HP

Article. 10.1038/s41698-024-00617-7. 2024

  • Open Access.

A review of machine learning methods for cancer characterization from microbiome data.

Teixeira, M; (...); Oliveira, HP

Review. 2024


Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects

Ferreira, RM; (...); Figueiredo, C

Article. 10.1093/infdis/jiac397. 2022


Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19

Salvador, P; (...); Malheiro, L

Article. 10.7759/cureus.13687. 2021

  • Open Access.

Clinical Features and Prognostic Factors of 245 Portuguese Patients Hospitalized With COVID-19.

Salvador, P; (...); Malheiro, L

Article. 2021


Combining nucleic acid mimics and spectral imaging with fluorescence in situ hybridization for the analysis of the gastric micro-biogeography

Azevedo, A. S.; (...); Azevedo, N.

Meeting Abstract. 2019


Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori

Ferreira, R; (...); Melo, LDR

Article. 10.3390/ijms23147885. 2022

  • Open Access.

Characterization and Genomic Analysis of a New Phage Infecting Helicobacter pylori.

Ferreira, R; (...); Melo, LDR

Article. 2022


E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner

Pereira, J; (...); Figueiredo, J

Article. 10.1186/s12964-024-01532-x. 2024

  • Open Access.

E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner.

Pereira, J; (...); Figueiredo, J

Article. 2024


Engineered liposomes to deliver nucleic acid mimics in Escherichia coli.

Moreira, L; (...); Azevedo, NF

Article. 2023


Engineered liposomes to deliver nucleic acid mimics in Escherichia coli

Moreira, L; (...); Azevedo, N.

Article. 10.1016/j.jconrel.2023.02.012. 2023

  • Open Access.

Enhancing Patient Safety and Access to Care to Populations at Risk of Exclusion: The Example of the Portuguese-Speaking Migrant Community in South London

Figueiredo, C; (...); Neves, A.AB -

Article. 10.20344/amp.12196. 2020

  • Open Access.

Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing

Pinto Ribeiro, I; (...); Figueiredo, C.

Article. 10.3390/ijms21031096. 2020

  • Open Access.

Evaluation of the Use of Formalin-Fixed and Paraffin-Embedded Archive Gastric Tissues for Microbiota Characterization Using Next-Generation Sequencing.

Pinto Ribeiro, I; (...); Figueiredo, C

Article. 2020


Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci

Cavadas, B; (...); Pereira, L

Article. 10.3390/microorganisms8081196. 2020

  • Open Access.

Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci.

Cavadas, B; (...); Pereira, L

Article. 2020


H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line

Malesp?n Benda?a, W; (...); Ram?rez, V

Article. 10.1007/s42770-023-00940-4. 2023

  • Open Access.

H elicobacter pylori infection induces abnormal expression of pro-angiogenic gene ANGPT2 and miR-203a in AGS gastric cell line.

Malespín Bendaña, W; (...); Ramírez, V

Article. 2023


Harnessing the Microbiome to Reduce Pancreatic Cancer Burden

Bastos, AR; (...); Figueiredo, C.

Review. 10.3390/cancers15092629. 2023

  • Open Access.

Harnessing the Microbiome to Reduce Pancreatic Cancer Burden.

Bastos, AR; (...); Figueiredo, C

Review. 2023


Helicobacter pylori infection: from standard to alternative treatment strategies

Sousa, C; (...); Melo, LDR

Article. 10.1080/1040841x.2021.1975643. 2022

  • Open Access.

Helicobacter pylori infection: from standard to alternative treatment strategies.

Sousa, C; (...); Melo, LDR

Review. 2022


Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays.

Silva, LM; (...); Palma, AS

Article. 2021


Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.

Marques, MS; (...); Figueiredo, C

Article. 2021


Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions

Leite, M; (...); Figueiredo, C.

Article. 10.3390/cells9020513. 2020

  • Open Access.

Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions.

Leite, M; (...); Figueiredo, C

Article. 2020


Integrin beta 1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells.

Figueiredo, J; (...); Seruca, R

Article. 2022


Integrin ß1 orchestrates the abnormal cell-matrix attachment and invasive behaviour of E-cadherin dysfunctional cells

Figueiredo, J; (...); Seruca, R

Article. 10.1007/s10120-021-01239-9. 2022

  • Open Access.

Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium

Melo, J; (...); Leite, M

Article. 10.3389/fmicb.2021.654193. 2021

  • Open Access.

Isolation Method and Characterization of Outer Membranes Vesicles of Helicobacter pylori Grown in a Chemically Defined Medium.

Melo, J; (...); Leite, M

Article. 2021


Machine learning-based approaches for cancer prediction using microbiome data.

Freitas, P; (...); Oliveira, HP

Article. 2023


Recent insights into the use of immune checkpoint inhibitors in gastric cancer

Rodrigues, S, Figueiredo, C.

Article. 10.1097/j.pbj.0000000000000162. 2022


Recent insights into the use of immune checkpoint inhibitors in gastric cancer.

Rodrigues, S, Figueiredo, C

Article. 2022


Review: Pathogenesis of Helicobacter pylori infection

Camargo, MC, Figueiredo, C., Machado, J.

Review. 10.1111/hel.12642. 2019


Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution

Bruno Cavadas; (...); Lu?sa Pereira

Article. 10.3390/microorganisms9020240. 2021

  • Open Access.

Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution.

Cavadas, B; (...); Pereira, L

Article. 2021


Systematic review: gastric microbiota in health and disease

Rajilic Stojanovic, M; (...); Hold, GL

Review. 10.1111/apt.15650. 2020


Systematic review: gastric microbiota in health and disease.

Rajilic Stojanovic, M; (...); Hold, GL

Review. 2020


The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes.

Thorell, K; (...); Rabkin, CS

Article. 2023


The Impact of SARS-CoV-2 Viral Load on the Mortality of Hospitalized Patients: A Retrospective Analysis.

Machado, A; (...); Malheiro, L

Article. 2021


The influence of the gastric microbiota in gastric cancer development

Pereira-Marques, J; (...); Figueiredo, C

Article. 10.1016/j.bpg.2021.101734. 2021


The influence of the gastric microbiota in gastric cancer development.

Pereira Marques, J; (...); Figueiredo, C

Article. 2021


The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally

Van Schooten, TS; (...); Fleitas, T

Article. 10.1186/s12885-022-09689-9. 2022

  • Open Access.

The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.

Van Schooten, TS; (...); Fleitas, T

Article. 2022


The Role of the Microbiota in Esophageal Cancer

Moreira, C, Figueiredo, C., Ferreira, RM

Article. 10.3390/cancers15092576. 2023

  • Open Access.

The Role of the Microbiota in Esophageal Cancer.

Moreira, C, Figueiredo, C, Ferreira, RM

Review. 2023


The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review

da Costa, CP; (...); Figueiredo, C.

Article. 10.3390/cancers14143385. 2022

  • Open Access.

The Tissue-Associated Microbiota in Colorectal Cancer: A Systematic Review.

da Costa, CP; (...); Figueiredo, C

Review. 2022


Transcriptomic remodeling of gastric cells by Helicobacter pylori outer membrane vesicles

Melo, J; (...); Leite, M

Article. 10.1111/hel.13031. 2023


Evaluation Of The Use Of Helicobacter Pylori Genotypes And Gastric Microbiota Markers To Identify Individuals At High Risk Of Gastric Carcinoma

Tese de doutoramento

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Harnessing The Microbiome To Reduce Pancreatic Cancer Burden

Trabalho final de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Helicobacter Pylori Eradication For Gastric Cancer Prevention

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Immune Checkpoint Inhibitors For The Treatment Of Gastric Cancer

Trabalho final de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Immune Checkpoint Inhibitors For The Treatment Of Gastric Cancer

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Systematic Review: The Mucosa-Associated Microbiota In Colorectal Cancer

Projeto de fim de curso

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


Systematic Review: The Mucosa-Associated Microbiota In Colorectal Cancer

Dissertação de Mestrado

Colaboradores: Maria do Céu Fontes Herdeiro Figueiredo


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