Portal de investigação
Gastric Cancer Morphological, Immunophenotypic and molecular heterogeneity
Dados básicos
- Código:
- Estudo Clínico Académico
- Protocolo:
- Estudo Clínico Académico
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2020
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays
Silva, LM; (...); Palma, AS
Article. 10.1016/j.carbpol.2020.117350. 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity
Marques, MS; (...); Figueiredo, C.
Article. 10.1080/19490976.2021.1921928. 2021
Helicobacter species binding to the human gastric mucosa
Matos, R; (...); Gärtner, F
Article. 10.1111/hel.12867. 2022
12-Gene Expression Signature: A Potential Key for Predicting Prognosis and Benefit to ACT for Resectable NSCLC Patients
Siqueira, A; (...); Leal, LF
Meeting Abstract. 2023
3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer
José, CS; (...); Oliveira, C
Article. 10.3390/biology12060803. 2023
A cost-effective model for the pathway of care of CDH1-related hereditary diffuse gastric cancer syndrome (HDGC)
Garrido, L; (...); Oliveira, C
Meeting Abstract. 2020
Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects
Ferreira, RM; (...); Figueiredo, C
Article. 10.1093/infdis/jiac397. 2022
Androgen-deprivation therapy and cognitive decline in the NEON-PC prospective study during the COVID-19 pandemic
Araujo, N; (...); Lunet, N.
Article. 10.1016/j.esmoop.2022.100448. 2022
Anxiety and Depression in Patients with Prostate Cancer, at Cancer Diagnosis and after a One-Year Follow-Up
Duarte, V; (...); Lunet, N.
Article. 10.3390/ijerph19159122. 2022
Association between sociodemographic and clinical features, health behaviors, and health literacy of patients with prostate cancer and prostate cancer prognostic stage
Braga, R; (...); Lunet, N
Article. 10.1097/cej.0000000000000854. 2023
Autoimmune hepatitis and eosinophilia: A rare case report
Garrido, I; (...); Macedo, G.
Article. 10.4254/wjh.v15.i2.311. 2023
CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer
Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients
Almeida, GM; (...); Oliveira, C
Article. 10.3390/biomedicines9091249. 2021
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients.
Article. 2021
Clinical databases and extended family pedigrees: the missing tool for intrafamilial risk estimation analysis
Meeting Abstract. 2024
Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis
Dal Cero, M; (...); de Manzoni, G
Review. 10.3390/cancers15215191. 2023
Colorectal Endoscopic Submucosal Dissection in a Western Center: Analysis of Outcomes and Safety Profile
Santos-Antunes, J; (...); Macedo, G
Article. 10.1159/000514797. 2021
Common variable immunodeficiency and gastric cancer: a study of morphology, virus infection and immunological microenvironment
Meeting Abstract. 2020
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness
Pereira, C; (...); Oliveira, C
Article. 10.1002/ijc.33872. 2022
Considerations in comparing intestinal- and diffuse-type gastric adenocarcinomas
Piazuelo, MB, Carneiro, F., Camargo, MC
Letter. 10.1111/hel.12975. 2023
Correlation between M30 immunochemistry and histological activity in steatohepatitis: One piece of a complex puzzle
Costa-Moreira, P; (...); Carneiro, F.
Letter. 10.1016/j.prp.2020.153191. 2020
Choosing the best approach for laterally spreading lesions at the anorectal junction
Santos-Antunes, J; (...); Macedo, G.
Letter. 10.1136/gutjnl-2020-322392. 2021
Decellularized Colorectal Cancer Matrices as Bioactive Scaffolds for Studying Tumor-Stroma Interactions
Marques Magalhaes, A; (...); Cardoso, AP
Review. 10.3390/cancers14020359. 2022
Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis
Article. 10.1093/ibd/izae204. 2024
Deployment of an artificial intelligence tool for precision medicine in ulcerative colitis: Preliminary data from 8 globally distributed clinical sites
Peyrin-Biroulet, L; (...); Kubassova, O
Meeting Abstract. 2023
DEPLOYMENT OF AN ARTIFICIAL INTELLIGENCE TOOL FOR PRECISION MEDICINE IN ULCERATIVE COLITIS: PRELIMINARY DATA FROM 8 GLOBALLY DISTRIBUTED CLINICAL SITES
Meeting Abstract. 2023
Detection of SARS-CoV-2 infection in thyroid follicular cells from a COVID-19 autopsy series
Macedo, S; (...); Soares Dias Ferreira, A.
Article. 10.1530/ETJ-22-0074. 2022
Diagnosis of digestive system tumours
Washington, MK; (...); Cree, IA
Review. 10.1002/ijc.33210. 2021
Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population
Matos, R; (...); Oliveira, C
Meeting Abstract. 2023
Dissecting the molecular mechanisms underlying therapy resistance and sensitivity in HER2-positive gastric cancer
Meeting Abstract. 2024
Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Gu?rin Immunotherapy
Article. 10.7759/cureus.50407. 2023
Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Guérin Immunotherapy.
Article. 2023
EBV and MSI Status in Gastric Cancer: Does It Matter?
do Nascimento, CN; (...); Carneiro, F.
Article. 10.3390/cancers15010074. 2023
ECCO Position Paper: Harmonization of the Approach to Ulcerative Colitis Histopathology
Magro, F.; (...); Feakins, R
Article. 10.1093/ecco-jcc/jjaa110. 2020
Engaging European society at the forefront of cancer research and care How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto
Baumann, M; (...); Wilking, N
Article. 10.1002/1878-0261.13423. 2023
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.
Article. 2022
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth
Santos, M; (...); Oliveira, C
Article. 10.3390/biology11071046. 2022
Epstein-Barr virus status drives morphological and molecular intra-tumour heterogeneity in gastric cancer: insights from a case report and literature review
Article. 10.1007/s00428-025-04035-3. 2025
Exosomal glypican-1 discriminates pancreatic ductal adenocarcinoma from chronic pancreatitis
Moutinho Ribeiro, P; (...); Macedo, G.
Article. 10.1016/j.dld.2021.10.012. 2022
Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities
Moutinho-Ribeiro, P; (...); Melo, SA
Article. 10.3748/wjg.v28.i31.4310. 2022
Expression of Thomsen-Friedenreich Antigen in Colorectal Cancer and Association with Microsatellite Instability
Leao, B; (...); Reis, CA
Article. 10.3390/ijms22031340. 2021
Expression of Thomsen-Friedenreich Antigen in Colorectal Cancer and Association with Microsatellite Instability.
Article. 2021
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
Ruivo, CF; (...); Melo, SA
Article. 10.1136/gutjnl-2021-324994. 2022
Familial and hereditary gastric cancer, an overview
Carneiro, F
Article. 10.1016/j.bpg.2022.101800. 2022
Fecal Dipeptidyl Peptidase-4: An Emergent Biomarker in Inflammatory Bowel Disease
Pinto Lopes, P; (...); Magro, F.
Article. 10.14309/ctg.0000000000000320. 2021
Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease
Meeting Abstract. 2024
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes
Garcia Pelaez, J; (...); Oliveira, C
Article. 10.1016/j.ejmg.2021.104401. 2022
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.
Article. 2022
Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Lordick, F; (...); ESMO Guidelines Committee
Article. 10.1016/j.annonc.2022.07.004. 2022
Gastric Polyps in Familial Adenomatous Polyposis Portuguese Patients: The First Western Cohort with Asian Features
Baptista, D; (...); Gullo, I
Article. 10.1159/000534571. 2023
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Garcia-Pelaez, J; (...); Oliveira, C
Article. 10.1016/S1470-2045(22)00643-X. 2023
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Meeting Abstract. 2024
Glycans as Immune Checkpoints: Removal of Branched N-glycans Enhances Immune Recognition Preventing Cancer Progression
Silva, MC; (...); Pinho, SS
Article. 10.1158/2326-6066.CIR-20-0264. 2020
Glycans as immune checkpoints: removal of branched N-glycans enhances immune recognition preventing cancer progression
Silva, MC; (...); Pinho, SS
Meeting Abstract. 2020
Hepatic amyloidosis: a prevalence study and clinical characterization of a rare and severe disease
Dias, E; (...); Macedo, G
Article. 10.17235/reed.2022.8622/2022. 2023
HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches
Article. 10.3390/cancers16061227. 2024
Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy
Magro, F.; (...); Carneiro, F.
Article. 10.1016/j.cgh.2020.09.017. 2021
Histologic Features of Syphilitic Gastritis A Rare but Resurging Imitator of Common Diseases
Assarzadegan, N; (...); Westerhoff, M
Article. 10.1093/ajcp/aqac153. 2023
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges
Garcia Pelaez, J; (...); Oliveira, C
Review. 10.1002/1878-0261.12948. 2021
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges.
Review. 2021
Ileal Crohn's Disease Exhibits Similar Transmural Fibrosis Irrespective of Phenotype
de Sousa, HT; (...); Magro, F
Article. 10.14309/ctg.0000000000000330. 2021
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development
Rocha, S; (...); Oliveira, C
Article. 10.3390/cancers13030421. 2021
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Article. 2021
Integrated multi-omics approaches uncover the landscape of gastric cancer in patients with diabetes mellitus
Meeting Abstract. 2024
Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis
Article. 10.1097/mpg.0000000000003877. 2024
Mechanobiology of Colorectal Cancer
Bras, MM; (...); Granja, PL
Review. 10.3390/cancers14081945. 2022
Merging patient-derived iPSCs and organ-on-a-chip technology to disclose the genesis of Hereditary Diffuse Gastric Cancer
Meeting Abstract. 2024
Mismatch repair protein and microsatellite instability status in gastric cancer: a comparative study between endoscopic biopsies and surgical specimens
Gullo, I; (...); Carneiro, F
Meeting Abstract. 2022
MISMATCH REPAIR PROTEIN STATUS IN GASTRIC CANCER CAN BE IDENTIFIED IN ENDOSCOPIC BIOPSIES AND DOES NOT SEEM TO INFLUENCE RESPONSE TO PERIOPERATIVE CHEMOTERAPY
Meeting Abstract. 2022
Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers
Bordeira-Carrico, R; (...); Bessa, J
Article. 10.1038/s41467-022-29551-7. 2022
Nodular Lymphoid Hyperplasia of the Rectum in a Patient With Primary Immunodeficiency
Santos-Antunes, J, Carneiro, F., Macedo, G.
Editorial Material. 10.14309/ajg.0000000000001032. 2021
Pancreatic cancer stem cell exosomes drive a hierarchical intratumor communication network that fuels disease progression through hippo pathway inhibition.
Ruivo, CF; (...); Melo, S
Meeting Abstract. 2021
Performance of immunohistochemical and molecular methods in detecting microsatellite instability in gastric cancer: a multicenter study
Marques, DS; (...); Carneiro, F.
Article. 10.1159/000530997. 2023
Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes
Gullo, I.; (...); Fassan, M
Review. 10.32074/1591-951X-166. 2020
Predicting residual neoplasia after a non-curative gastric ESD: validation and modification of the eCura system in the Western setting: the W-eCura score
Morais, R; (...); Santos-Antunes, J
Article. 10.1136/gutjnl-2023-330804. 2023
Presence of Helicobacter Species in Gastric Mucosa of Human Patients and Outcome of Helicobacter Eradication Treatment
Matos, R; (...); Gaertner, F
Article. 10.3390/jpm12020181. 2022
Prevalence of Cognitive Impairment before Prostate Cancer Treatment
Ara?jo, N.; (...); Lunet, N.
Article. 10.3390/cancers14051355. 2022
Primary gastric choriocarcinoma: a rare and aggressive gastrointestinal malignancy
Dias, E; (...); Macedo, G.
Letter. 10.17235/reed.2022.9433/2022. 2023
Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression
Moreira, AM; (...); Seruca, R
Article. 10.3389/fmolb.2022.818552. 2022
Proteomics Analysis of Gastric Cancer Patients with Diabetes Mellitus
Osorio, H; (...); Carneiro, F.
Article. 10.3390/jcm10030407. 2021
Real-world data of perioperative FLOT in resectable gastric and gastro-esophagic junction cancer: The experience of a Portuguese institution
Meeting Abstract. 10.1016/j.annonc.2022.04.376. 2022
Recent advances in the pathology of heritable gastric cancer syndromes
Gullo, I., van der Post, RS, Carneiro, F.
Article. 10.1111/his.14228. 2021
Reproducibility of a 12-gene panel and development of user-friendly nomogram-based calculator for clinical management of surgically resected non-small cell lung cancer patients.
Meeting Abstract. 2021
Reproducibility of a 12-gene set for predicting outcome and benefit from ACT in earlystage NSCLC patients
Meeting Abstract. 10.1183/13993003.congress-2023.OA1451. 2023
Retrospective analysis of the outcomes of endoscopic submucosal dissection for the diagnosis and treatment of subepithelial lesions in a center with high expertise
Santos-Antunes, J; (...); Macedo, G
Article. 10.20524/aog.2021.0675. 2022
Role of Endoscopic Biopsies and Morphologic Features in Predicting Microsatellite Instability Status in Gastric Cancer : A Multicenter Comparative Study of Endoscopic Biopsies and Surgical Specimens
Silva, R; (...); Gullo, I
Article. 10.1097/PAS.0000000000002085. 2023
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing
Barbosa Matos, R; (...); Oliveira, C
Article. 10.3390/cancers13174464. 2021
The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence
Freitas, JA; (...); Machado, J.
Article. 10.3390/ijms22189791. 2021
The autopsy of Napoleon Bonaparte: Anatomo-pathological assessment for the bicentenary of the death of Napoleon I on the island of Saint Helena in 1821
Lugli, A; (...); Svrcek, M
Article. 10.1016/j.annpat.2021.04.004. 2021
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing.
Article. 2021
The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction
Melo, S; (...); Travasso, DM
Article. 10.1038/s42003-023-05482-x. 2023
THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING
Barbosa-Matos, R; (...); Oliveira, C
Meeting Abstract. 2022
The gastric disease of Napoleon Bonaparte: brief report for the bicentenary of Napoleon's death on St. Helena in 1821
Lugli, A; (...); Svrcek, M
Article. 10.1007/s00428-021-03061-1. 2021
The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally
Van Schooten, TS; (...); Fleitas, T
Article. 10.1186/s12885-022-09689-9. 2022
The Porto European Cancer Research Summit 2021
Ringborg, U; (...); Zitvogel, L
Article. 10.1002/1878-0261.13078. 2021
Thermal injury in tonsils and its relation to postoperative pain-a histopathological and clinical study
Obeidat, M; (...); Spratley, J
Article. 10.1186/s43163-021-00089-7. 2021
Towards Automatic Protein Co-Expression Quantification in Immunohistochemical TMA Slides
Solorzano, L; (...); Wahlby, C
Article. 10.1109/JBHI.2020.3008821. 2021
Transmural Histological Scoring Systems in Crohn's Disease: A Systematic Review With Assessment of Methodological Quality and Operating Properties (vol 14, pg 743, 2020)
de Sousa, HT; (...); Magro, F
Correction. 2021
Tumor regression grading after neoadjuvant treatment of esophageal and gastroesophageal junction adenocarcinoma: results of an international Delphi consensus survey
Saliba, G; (...); Klevebro, F
Article. 10.1016/j.humpath.2020.11.001. 2021
Understanding progression of strictures in ileal Crohn's disease-The importance of setting methodological standards
de Sousa, HT, Carneiro, F.
Editorial Material. 10.1002/ueg2.12327. 2022
Undifferentiated embryonal sarcoma of the liver: A rare hepatic tumor and its related characteristic radiological features
Gomes, F; (...); Oliveira, P
Article. 10.1016/j.radcr.2020.12.017. 2021
Validation of a 5-gene signature for predicting outcomes in early-stage NSCLC patients
Meeting Abstract. 10.1183/13993003.congress-2023.OA1449. 2023
Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience
Santos-Antunes, J; (...); Macedo, G.
Article. 10.1097/MEG.0000000000002047. 2021
