Portal de investigação
Gastric Cancer Morphological, Immunophenotypic and molecular heterogeneity
Dados básicos
- Código:
- Estudo Clínico Académico
- Protocolo:
- Estudo Clínico Académico
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2020
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays
Silva, LM; (...); Palma, AS
Article. 10.1016/j.carbpol.2020.117350. 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity
Marques, MS; (...); Figueiredo, C.
Article. 10.1080/19490976.2021.1921928. 2021
Helicobacter species binding to the human gastric mucosa
Matos, R; (...); Gärtner, F
Article. 10.1111/hel.12867. 2022
12-Gene Expression Signature: A Potential Key for Predicting Prognosis and Benefit to ACT for Resectable NSCLC Patients
Siqueira, A; (...); Leal, LF
Meeting Abstract. 2023
3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer
José, CS; (...); Oliveira, C
Article. 10.3390/biology12060803. 2023
A cost-effective model for the pathway of care of CDH1-related hereditary diffuse gastric cancer syndrome (HDGC)
Garrido, L; (...); Oliveira, C
Meeting Abstract. 2020
Activation of Laminin ?2 by Helicobacter pylori Promotes Invasion and Survival of Gastric Cancer Cells With E-Cadherin Defects
Ferreira, RM; (...); Figueiredo, C
Article. 10.1093/infdis/jiac397. 2022
Androgen-deprivation therapy and cognitive decline in the NEON-PC prospective study during the COVID-19 pandemic
Araujo, N; (...); Lunet, N.
Article. 10.1016/j.esmoop.2022.100448. 2022
Anxiety and Depression in Patients with Prostate Cancer, at Cancer Diagnosis and after a One-Year Follow-Up
Duarte, V; (...); Lunet, N.
Article. 10.3390/ijerph19159122. 2022
Association between sociodemographic and clinical features, health behaviors, and health literacy of patients with prostate cancer and prostate cancer prognostic stage
Braga, R; (...); Lunet, N
Article. 10.1097/cej.0000000000000854. 2023
Autoimmune hepatitis after COVID-19 vaccine-more than a coincidence.
Garrido, I; (...); Macedo, G
Article. 2021
Autoimmune hepatitis and eosinophilia: A rare case report
Garrido, I; (...); Macedo, G.
Article. 10.4254/wjh.v15.i2.311. 2023
CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer
Park, Ji-Hyeon; (...); Oliveira, Carla
Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients
Almeida, GM; (...); Oliveira, C
Article. 10.3390/biomedicines9091249. 2021
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients.
Almeida, GM; (...); Oliveira, C
Article. 2021
Clinical databases and extended family pedigrees: the missing tool for intrafamilial risk estimation analysis
Fonseca, Joao; (...); Oliveira, Carla
Meeting Abstract. 2024
Clinical Features of Gastric Signet Ring Cell Cancer: Results from a Systematic Review and Meta-Analysis
Dal Cero, M; (...); de Manzoni, G
Review. 10.3390/cancers15215191. 2023
Colorectal Endoscopic Submucosal Dissection in a Western Center: Analysis of Outcomes and Safety Profile
Santos-Antunes, J; (...); Macedo, G
Article. 10.1159/000514797. 2021
Common variable immunodeficiency and gastric cancer: a study of morphology, virus infection and immunological microenvironment
Costa, C.; (...); Carneiro, F.
Meeting Abstract. 2020
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness
Pereira, C; (...); Oliveira, C
Article. 10.1002/ijc.33872. 2022
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness.
Pereira, C; (...); Oliveira, C
Article. 2022
Considerations in comparing intestinal- and diffuse-type gastric adenocarcinomas
Piazuelo, MB, Carneiro, F., Camargo, MC
Letter. 10.1111/hel.12975. 2023
Correlation between M30 immunochemistry and histological activity in steatohepatitis: One piece of a complex puzzle
Costa-Moreira, P; (...); Carneiro, F.
Letter. 10.1016/j.prp.2020.153191. 2020
Choosing the best approach for laterally spreading lesions at the anorectal junction
Santos-Antunes, J; (...); Macedo, G.
Letter. 10.1136/gutjnl-2020-322392. 2021
Decellularized Colorectal Cancer Matrices as Bioactive Scaffolds for Studying Tumor-Stroma Interactions
Marques Magalhaes, A; (...); Cardoso, AP
Review. 10.3390/cancers14020359. 2022
Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis
Rubin, David T.; (...); Peyrin-Biroulet, Laurent
Article. 10.1093/ibd/izae204. 2024
Deployment of an artificial intelligence tool for precision medicine in ulcerative colitis: Preliminary data from 8 globally distributed clinical sites
Peyrin-Biroulet, L; (...); Kubassova, O
Meeting Abstract. 2023
DEPLOYMENT OF AN ARTIFICIAL INTELLIGENCE TOOL FOR PRECISION MEDICINE IN ULCERATIVE COLITIS: PRELIMINARY DATA FROM 8 GLOBALLY DISTRIBUTED CLINICAL SITES
Rubin, David T.; (...); Kubassova, Olga
Meeting Abstract. 2023
Detection of SARS-CoV-2 infection in thyroid follicular cells from a COVID-19 autopsy series
Macedo, S; (...); Soares Dias Ferreira, A.
Article. 10.1530/ETJ-22-0074. 2022
Diagnosis of digestive system tumours
Washington, MK; (...); Cree, IA
Review. 10.1002/ijc.33210. 2021
Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population
Matos, R; (...); Oliveira, C
Meeting Abstract. 2023
Dissecting the molecular mechanisms underlying therapy resistance and sensitivity in HER2-positive gastric cancer
Fernandes Neto, Joao M.; (...); Oliveira, Carla
Meeting Abstract. 2024
Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Gu?rin Immunotherapy
Mendes, MH; (...); Santos, L.
Article. 10.7759/cureus.50407. 2023
Disseminated Mycobacterium bovis Infection: A Rare Complication of Bacillus Calmette-Guérin Immunotherapy.
Mendes, MH; (...); santos, l
Article. 2023
EBV and MSI Status in Gastric Cancer: Does It Matter?
do Nascimento, CN; (...); Carneiro, F.
Article. 10.3390/cancers15010074. 2023
ECCO Position Paper: Harmonization of the Approach to Ulcerative Colitis Histopathology
Magro, F.; (...); Feakins, R
Article. 10.1093/ecco-jcc/jjaa110. 2020
Engaging European society at the forefront of cancer research and care How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto
Baumann, M; (...); Wilking, N
Article. 10.1002/1878-0261.13423. 2023
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.
Santos, M; (...); Oliveira, C
Article. 2022
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth
Santos, M; (...); Oliveira, C
Article. 10.3390/biology11071046. 2022
Epstein-Barr virus status drives morphological and molecular intra-tumour heterogeneity in gastric cancer: insights from a case report and literature review
Gullo, Irene; (...); Carneiro, Fatima
Article. 10.1007/s00428-025-04035-3. 2025
Exosomal glypican-1 discriminates pancreatic ductal adenocarcinoma from chronic pancreatitis
Moutinho Ribeiro, P; (...); Macedo, G.
Article. 10.1016/j.dld.2021.10.012. 2022
Exosomal glypican-1 is elevated in pancreatic cancer precursors and can signal genetic predisposition in the absence of endoscopic ultrasound abnormalities
Moutinho-Ribeiro, P; (...); Melo, SA
Article. 10.3748/wjg.v28.i31.4310. 2022
Expression of Thomsen-Friedenreich Antigen in Colorectal Cancer and Association with Microsatellite Instability
Leao, B; (...); Reis, CA
Article. 10.3390/ijms22031340. 2021
Expression of Thomsen-Friedenreich Antigen in Colorectal Cancer and Association with Microsatellite Instability.
Leao, B; (...); Reis, CA
Article. 2021
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
Ruivo, CF; (...); Melo, SA
Article. 10.1136/gutjnl-2021-324994. 2022
Familial and hereditary gastric cancer, an overview
Carneiro, F
Article. 10.1016/j.bpg.2022.101800. 2022
Fecal Dipeptidyl Peptidase-4: An Emergent Biomarker in Inflammatory Bowel Disease
Pinto Lopes, P; (...); Magro, F.
Article. 10.14309/ctg.0000000000000320. 2021
Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease
De Sousa, H. Tavares; (...); Magro, F.
Meeting Abstract. 2024
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes
Garcia Pelaez, J; (...); Oliveira, C
Article. 10.1016/j.ejmg.2021.104401. 2022
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.
Garcia Pelaez, J; (...); Oliveira, C
Article. 2022
Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Lordick, F; (...); ESMO Guidelines Committee
Article. 10.1016/j.annonc.2022.07.004. 2022
Gastric Polyps in Familial Adenomatous Polyposis Portuguese Patients: The First Western Cohort with Asian Features
Baptista, D; (...); Gullo, I
Article. 10.1159/000534571. 2023
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Garcia-Pelaez, J; (...); Oliveira, C
Article. 10.1016/S1470-2045(22)00643-X. 2023
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Garcia-Pelaez, J.; (...); Oliveira, Carla
Meeting Abstract. 2024
Glycans as Immune Checkpoints: Removal of Branched N-glycans Enhances Immune Recognition Preventing Cancer Progression
Silva, MC; (...); Pinho, SS
Article. 10.1158/2326-6066.CIR-20-0264. 2020
Glycans as immune checkpoints: removal of branched N-glycans enhances immune recognition preventing cancer progression
Silva, MC; (...); Pinho, SS
Meeting Abstract. 2020
Helicobacter pylori lipopolysaccharide structural domains and their recognition by immune proteins revealed with carbohydrate microarrays.
Silva, LM; (...); Palma, AS
Article. 2021
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.
Marques, MS; (...); Figueiredo, C
Article. 2021
Hepatic amyloidosis: a prevalence study and clinical characterization of a rare and severe disease
Dias, E; (...); Macedo, G
Article. 10.17235/reed.2022.8622/2022. 2023
HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches
Freitas, MB; (...); Duarte, HO
Article. 10.3390/cancers16061227. 2024
Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy
Magro, F.; (...); Carneiro, F.
Article. 10.1016/j.cgh.2020.09.017. 2021
Histologic Features of Syphilitic Gastritis A Rare but Resurging Imitator of Common Diseases
Assarzadegan, N; (...); Westerhoff, M
Article. 10.1093/ajcp/aqac153. 2023
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges
Garcia Pelaez, J; (...); Oliveira, C
Review. 10.1002/1878-0261.12948. 2021
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges.
Garcia Pelaez, J; (...); Oliveira, C
Review. 2021
Ileal Crohn's Disease Exhibits Similar Transmural Fibrosis Irrespective of Phenotype
de Sousa, HT; (...); Magro, F
Article. 10.14309/ctg.0000000000000330. 2021
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development
Rocha, S; (...); Oliveira, C
Article. 10.3390/cancers13030421. 2021
Immunophenotype of Gastric Tumors Unveils a Pleiotropic Role of Regulatory T Cells in Tumor Development.
Rocha, S; (...); Oliveira, C
Article. 2021
Integrated multi-omics approaches uncover the landscape of gastric cancer in patients with diabetes mellitus
Ferreira, Marta; (...); Oliveira, Carla
Meeting Abstract. 2024
Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis
Papadopoulou, A; (...); Furuta, GT
Article. 10.1097/mpg.0000000000003877. 2024
Mechanobiology of Colorectal Cancer
Bras, MM; (...); Granja, PL
Review. 10.3390/cancers14081945. 2022
Merging patient-derived iPSCs and organ-on-a-chip technology to disclose the genesis of Hereditary Diffuse Gastric Cancer
Ferreira, Daniel A.; (...); Oliveira, Carla
Meeting Abstract. 2024
Mismatch repair protein and microsatellite instability status in gastric cancer: a comparative study between endoscopic biopsies and surgical specimens
Gullo, I; (...); Carneiro, F
Meeting Abstract. 2022
MISMATCH REPAIR PROTEIN STATUS IN GASTRIC CANCER CAN BE IDENTIFIED IN ENDOSCOPIC BIOPSIES AND DOES NOT SEEM TO INFLUENCE RESPONSE TO PERIOPERATIVE CHEMOTERAPY
Nascimento, Catarina N.; (...); Carneiro, Fatima
Meeting Abstract. 2022
Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers
Bordeira-Carrico, R; (...); Bessa, J
Article. 10.1038/s41467-022-29551-7. 2022
Nodular Lymphoid Hyperplasia of the Rectum in a Patient With Primary Immunodeficiency
Santos-Antunes, J, Carneiro, F., Macedo, G.
Editorial Material. 10.14309/ajg.0000000000001032. 2021
Pancreatic cancer stem cell exosomes drive a hierarchical intratumor communication network that fuels disease progression through hippo pathway inhibition.
Ruivo, CF; (...); Melo, S
Meeting Abstract. 2021
Performance of immunohistochemical and molecular methods in detecting microsatellite instability in gastric cancer: a multicenter study
Marques, DS; (...); Carneiro, F.
Article. 10.1159/000530997. 2023
Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes
Gullo, I.; (...); Fassan, M
Review. 10.32074/1591-951X-166. 2020
Predicting residual neoplasia after a non-curative gastric ESD: validation and modification of the eCura system in the Western setting: the W-eCura score
Morais, R; (...); Santos-Antunes, J
Article. 10.1136/gutjnl-2023-330804. 2023
Presence of Helicobacter Species in Gastric Mucosa of Human Patients and Outcome of Helicobacter Eradication Treatment
Matos, R; (...); Gaertner, F
Article. 10.3390/jpm12020181. 2022
Prevalence of Cognitive Impairment before Prostate Cancer Treatment
Ara?jo, N.; (...); Lunet, N.
Article. 10.3390/cancers14051355. 2022
Primary gastric choriocarcinoma: a rare and aggressive gastrointestinal malignancy
Dias, E; (...); Macedo, G.
Letter. 10.17235/reed.2022.9433/2022. 2023
Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression
Moreira, AM; (...); Seruca, R
Article. 10.3389/fmolb.2022.818552. 2022
Proteomics Analysis of Gastric Cancer Patients with Diabetes Mellitus
Osorio, H; (...); Carneiro, F.
Article. 10.3390/jcm10030407. 2021
Real-world data of perioperative FLOT in resectable gastric and gastro-esophagic junction cancer: The experience of a Portuguese institution
Vilas-Boas, M.; (...); Fragoso, M.
Meeting Abstract. 10.1016/j.annonc.2022.04.376. 2022
Recent advances in the pathology of heritable gastric cancer syndromes
Gullo, I., van der Post, RS, Carneiro, F.
Article. 10.1111/his.14228. 2021
Recent advances in the pathology of heritable gastric cancer syndromes.
Gullo, I, van der Post, RS, Carneiro, F
Article. 2021
Reproducibility of a 12-gene panel and development of user-friendly nomogram-based calculator for clinical management of surgically resected non-small cell lung cancer patients.
Leal, Leticia Ferro; (...); Reis, Rui M.
Meeting Abstract. 2021
Reproducibility of a 12-gene set for predicting outcome and benefit from ACT in earlystage NSCLC patients
Siqueira, Alexia Polo; (...); Reis, Rui
Meeting Abstract. 10.1183/13993003.congress-2023.OA1451. 2023
Retrospective analysis of the outcomes of endoscopic submucosal dissection for the diagnosis and treatment of subepithelial lesions in a center with high expertise
Santos-Antunes, J; (...); Macedo, G
Article. 10.20524/aog.2021.0675. 2022
Role of Endoscopic Biopsies and Morphologic Features in Predicting Microsatellite Instability Status in Gastric Cancer : A Multicenter Comparative Study of Endoscopic Biopsies and Surgical Specimens
Silva, R; (...); Gullo, I
Article. 10.1097/PAS.0000000000002085. 2023
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing
Barbosa Matos, R; (...); Oliveira, C
Article. 10.3390/cancers13174464. 2021
The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence
Freitas, JA; (...); Machado, J.
Article. 10.3390/ijms22189791. 2021
The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence.
Freitas, JA; (...); Machado, JC
Article. 2021
The autopsy of Napoleon Bonaparte: Anatomo-pathological assessment for the bicentenary of the death of Napoleon I on the island of Saint Helena in 1821
Lugli, A; (...); Svrcek, M
Article. 10.1016/j.annpat.2021.04.004. 2021
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing.
Barbosa Matos, R; (...); Oliveira, C
Article. 2021
The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction
Melo, S; (...); Travasso, DM
Article. 10.1038/s42003-023-05482-x. 2023
THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING
Barbosa-Matos, R; (...); Oliveira, C
Meeting Abstract. 2022
The gastric disease of Napoleon Bonaparte: brief report for the bicentenary of Napoleon's death on St. Helena in 1821
Lugli, A; (...); Svrcek, M
Article. 10.1007/s00428-021-03061-1. 2021
The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally
Van Schooten, TS; (...); Fleitas, T
Article. 10.1186/s12885-022-09689-9. 2022
The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally.
Van Schooten, TS; (...); Fleitas, T
Article. 2022
The Porto European Cancer Research Summit 2021
Ringborg, U; (...); Zitvogel, L
Article. 10.1002/1878-0261.13078. 2021
Thermal injury in tonsils and its relation to postoperative pain-a histopathological and clinical study
Obeidat, M; (...); Spratley, J
Article. 10.1186/s43163-021-00089-7. 2021
Towards Automatic Protein Co-Expression Quantification in Immunohistochemical TMA Slides
Solorzano, L; (...); Wahlby, C
Article. 10.1109/JBHI.2020.3008821. 2021
Transmural Histological Scoring Systems in Crohn's Disease: A Systematic Review With Assessment of Methodological Quality and Operating Properties (vol 14, pg 743, 2020)
de Sousa, HT; (...); Magro, F
Correction. 2021
Tumor regression grading after neoadjuvant treatment of esophageal and gastroesophageal junction adenocarcinoma: results of an international Delphi consensus survey
Saliba, G; (...); Klevebro, F
Article. 10.1016/j.humpath.2020.11.001. 2021
Understanding progression of strictures in ileal Crohn's disease-The importance of setting methodological standards
de Sousa, HT, Carneiro, F.
Editorial Material. 10.1002/ueg2.12327. 2022
Undifferentiated embryonal sarcoma of the liver: A rare hepatic tumor and its related characteristic radiological features
Gomes, F; (...); Oliveira, P
Article. 10.1016/j.radcr.2020.12.017. 2021
Validation of a 5-gene signature for predicting outcomes in early-stage NSCLC patients
Miranda, Keila Cristina; (...); Reis, Rui
Meeting Abstract. 10.1183/13993003.congress-2023.OA1449. 2023
Very low rate of residual neoplasia after non-curative endoscopic submucosal dissection: a western single-center experience
Santos-Antunes, J; (...); Macedo, G.
Article. 10.1097/MEG.0000000000002047. 2021
